Telomere & Telomerase Analysis Technology

Our cutting-edge technology for a comprehensive Telomere Analysis
through determination of multiple Telomere Associated Variables (TAVs).

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TAT DETERMINES

Mean and Median Telomere Length
Lowest 20^thpercentile Telomere Length
% short telomeres
% of cells with short telomeres
Full Telomere Length histogram distribution
Absolute measurements in base pairs

KEY FACTS

Clinically Validated (CLIA and ISO 15189)
Simultaneous processing of hundreds of samples (384 plates)
Can be performed on any cell type
Intra-assay coefficient of variation <5%
Seven control cell lines
Each sample is run in quintuplicate
Thousands of telomeres measured per sample
High throughput quantitative fluorescence in situ hybridization technology (HT Q-FISH)

TAT can process multiple types of samples

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Some examples are:

Blood
Stem Cells
Fibroblast cells
Sperm
Solid tumors
Several tissue samples
Bone marrow

Telomerase is the enzyme that can elongate telomeres and it can be used as an independent biomarker or in combination with other Telomere variables. The Q-TRAP assay measures the activity of the telomerase enzyme.

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KEY FACTS

Clinically Validated (CLIA and ISO 15189)
Simultaneous processing of hundreds of samples (384 plates)
Each sample is run in triplicate
Ideal for screening telomerase inhibitor and/or activator compounds
Full study report with statistical analysis
Quantitative Telomeric Repeat Amplification Protocol Technology (Q-TRAP)

Q-TRAP can process different types of samples

Some examples are: Blood, any type of stem cell, fibroblast cells, cancer cells, etc.

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An alternative Telomere Length assay ideal for isolated DNA samples.

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KEY FACTS

Relative and absolute telomere length measurements (T/S ratio and in base pairs)
Simultaneous processing of hundreds of samples (384 plates)
Each sample is run in triplicate
Applicable for purified isolated DNA of any biological sample
Optimized for human sample processing
Quantitative Polimerase chain reaction (qPCR)

The “Gold Standard” for Telomere Length determination